I'm a couple of sessions now into a plain vanilla Eberron game using drobertson's racial backgrounds, and probably more of his houserules later. The first batch of players are my kids, with some friends joining in shortly from a True20 EPT campaign thanks to evil NPC wizards who want to get rid of them. As a GM, my style is oriented towards pulp and action adventure movies, so the setting and rules both work well. I'm letting people "grow into" their vices and virtues, so these aren't fully defined yet.
The initial PCs:
Eleanora Miso (the obligatory hobbit thief; Halfling Expert 1). Ellie ran away to Sharn after borrowing a prize dinosaur (which has yet to appear in play). Virtue: TBA, but probably Friendly. Vice: Soup addict.
Chunkerley (Warforged Warrior 1). Chunkerley tooled up with Adamantium armour, and boosted Str, Dex and Con to +5. Unfortunately, while this makes him a combat god, it drops his Wis and Cha to -5, and thus his Wealth to 0. Consequently he follows Eleanora around, because she used her massive edge in Cha and Wis to Intimidate him. She now uses him to Intimidate others (Chunkerley: "You'd better do what the halfling says, she's really scary!") Virtue: TBA. Vice: Trigger-happy.
Pasha Islech (NPC Adept 1). Virtue: TBA. Vice: Fastidious. It seemed obvious they were going to need Cure a lot, and didn't have it; hence an NPC healer. Then I realised that an Adept didn't have to be either a Wizard or a Cleric (we spent the last couple of years playing D&D together), so added Fire Shaping, Heart Shaping, and Elemental Blast (for later levels).
Suetonius (at least until a better name comes along; Expert 1). Suetonius is a young nobleman of Sharn, heavy on interpersonal skills and vehicle/animal skills. He's likely to be a recurring "guest star" as the player has left home now. Virtue: Honour. Vice: Drink problem.